mié, 21 oct 2026 · Salud de la mujer
Chaste tree
Vitex agnus-castus
A Mediterranean shrub whose pepper-like berries connect ancient women’s remedies with modern research on premenstrual symptoms.
Dónde actúa en el cuerpo
- Reproductivo
- Cerebro
Sabiduría tradicional
Para quienes se inician en el Ayurveda
Vitex agnus-castus has no established classical Sanskrit identity; Nirgundi ordinarily refers to Vitex negundo, a different species. The energetics given here are a contemporary Ayurvedic interpretation, not a classical attribution, and powdered chaste-tree fruit should not be represented as a classical Nirgundi churna or kashaya.
Sabor (rasa)
Equilibrio de los doshas
En distintas tradiciones
Contemporary Ayurvedic herbalists sometimes interpret the fruit as bitter-pungent and warming, tending to settle vata and kapha while increasing pitta. Its use for menstrual concerns is an incorporation of Western herbal practice, rather than an established classical Ayurvedic indication.
Ritual consciente
Pause beside a living chaste tree, or contemplate a picture of its violet flower spikes, and take three unhurried breaths. Let the ritual be one of attention rather than an invitation to self-prescribe a hormone-active herb.
Principios activos
- DiterpenesSome isolated diterpenes show dopamine-receptor activity in laboratory studies, a possible contributor to effects on prolactin signaling.
- AgnusideAn iridoid glycoside used as a quality-control marker; its independent contribution to clinical benefits remains uncertain.
- CasticinA flavonoid used in extract characterization, with anti-inflammatory activity in laboratory research; its clinical contribution is unclear. Visual compound weights are illustrative emphasis, not measured composition or proven contributions to benefit.
Investigación moderna
De cerca
Dónde crece
¿Es seguro para mí?
Sobre la planta
Chaste tree is a deciduous shrub or small tree in the mint family, native to the Mediterranean region and western Asia. It grows along streams and other seasonally moist places, and is cultivated in sunny gardens worldwide.
Its aromatic leaves divide into five to seven narrow leaflets, and its upright spikes carry small lilac to violet flowers. The flowers develop into dark, peppercorn-sized fruits, commonly called chasteberries, which are the principal medicinal part.
El descubrimiento
Ancient Greek and Roman writers described chaste tree in connection with reproductive health and chastity; its reputation for suppressing sexual desire helped give it its common name, but that reputation is not established clinical evidence. European herbal traditions later used the fruits for menstrual complaints. Modern researchers investigated standardized fruit extracts after clinical observations suggested benefits for premenstrual symptoms, exploring effects on dopamine signaling and prolactin regulation rather than assuming that the berries simply supply female hormones.
Usos tradicionales
- Relief of premenstrual discomfort, including irritability and breast tenderness.
- Support for irregular menstrual cycles.
- Use for menstrual-associated breast pain.
- Historical use to influence milk production; effectiveness and safety during breastfeeding are not established.
Detalles de la investigación
Premenstrual symptom relief · Preliminar
None of the supplied excerpts directly reports results for premenstrual symptom relief. The adolescent menstrual-disorder case series does not identify premenstrual symptom outcomes in the provided text.
Cyclic breast pain relief · Preliminar
None of the supplied sources directly evaluates cyclic breast pain relief, so benefit or lack of benefit cannot be established from this source set.
Fertility support · Preliminar
None of the supplied excerpts directly reports fertility outcomes such as ovulation, pregnancy, or live birth. The PCOS studies examine hormonal, metabolic, or menstrual measures, which do not establish improved fertility; the human trial excerpts also omit results.
Cómo se usa
- If considering it for PMS, choose a quality-tested fruit extract that specifies its preparation and standardization. Different extract strengths are not interchangeable.
- Some studied and European-authorized preparations use 20 mg of a specific dry extract once daily. This is not equivalent to 20 mg of powdered berries; follow the particular product instructions and professional advice.
- Track symptoms over two to three menstrual cycles and reassess after about three months. Seek advice if symptoms persist, worsen, or substantially affect daily life.
- Capsules, tablets, and tinctures are common preparations, but evidence mainly concerns particular extracts—not homemade berry tea.
Seguridad
- Possible adverse effects include nausea, abdominal discomfort, headache, acne, rash, and changes in menstrual bleeding.
- Avoid during pregnancy and breastfeeding. It is generally not recommended for children or adolescents without specialist advice.
- Consult a clinician first if you have a hormone-sensitive condition or a pituitary disorder. Chasteberry may affect prolactin regulation and could complicate assessment of an underlying problem.
- Long-term safety is not well established. Severe mood symptoms, unexplained bleeding, a breast lump, or persistent breast pain need medical evaluation.
Interacciones con medicamentos
- Possible interaction with hormonal contraceptives: clinical evidence is limited, but an effect on contraceptive action cannot be excluded. Discuss use with a pharmacist or prescriber.
- May interact with hormone therapy, fertility medicines, or antiestrogen treatments such as tamoxifen; avoid combining without specialist guidance.
- May oppose or alter the effects of dopamine-related medicines, including antipsychotics, metoclopramide, and dopamine agonists such as cabergoline.
Fuentes
Elaborado a partir de 10 fuentes, seleccionadas según reglas fijas, no por la IA.
Estudios en humanos
- [1]The effects of <i>Vitex agnus-castus</i> supplementation on inflammatory markers in women with PCOS: a randomized, double-blind, placebocontrolled trial
Research in pharmaceutical sciences · 2026
EnsayoMotivo: Randomised human trial, 2026, recent, human data - [2]The Effect of Vitex Agnus - Castus Plant on Some Markers of Oxidative Stress, Lipid Profile and Insulin Resistance in Women with Polycystic Ovary Syndrome: A Randomized, Double-Blind Controlled Clinical Trial Study
JBRA assisted reproduction · 2026
EnsayoMotivo: Randomised human trial, 2026, recent, human data - [3]Case Series: Real-Life Experience with Vitex Agnus-Castus Extract Ze 440 Medication in Adolescents
Complementary medicine research · 2026
Estudio en humanosMotivo: Human study, 2026, recent, human data
Revisiones e investigación de laboratorio
- [4]Deep Eutectic Solvent Based Microwave and Ultrasound Assisted Extraction of Bioactive Compounds From Vitex agnus-castus: Optimization and Antioxidant/Antibacterial Evaluation
Chemistry & biodiversity · 2026
Laboratorio / animalesMotivo: Lab or animal study, 2026, recent, not in people - [5]Clinical evaluation of the efficacy of <i>Vitex agnus-castus</i> compared with cabergoline for the treatment of pseudopregnancy in the bitch
Frontiers in veterinary science · 2026
Laboratorio / animalesMotivo: Lab or animal study, 2026, recent, not in people - [6]<i>Vitex Agnus-Castus</i> Extract Supplementation Enhanced Growth Performance, Hemato-Biochemical Parameters, Intestinal Histomorphometry, Flesh Composition, and Quality of Nile Tilapia, <i>Oreochromis niloticus</i>
Aquaculture nutrition · 2026
Laboratorio / animalesMotivo: Lab or animal study, 2026, recent, not in people - [7]<i>Vitex agnus-castus</i> extract improved the endocrine profile and important gene expression in rat ovaries with polycystic ovary syndrome
Avicenna journal of phytomedicine · 2026
Laboratorio / animalesMotivo: Lab or animal study, 2026, recent, not in people - [8]Immunomodulatory effects of dietary chaste tree (<i>Vitex agnus-castus</i> L.) extract in rainbow trout (<i>Oncorhynchus mykiss</i>)
Open veterinary journal · 2025
Laboratorio / animalesMotivo: Lab or animal study, 2025, recent, not in people - [9]Anticancer Activity of <i>Vitex agnus-castus</i> Seed Extract on Gastric Cancer Cells
Nutrients · 2025
Laboratorio / animalesMotivo: Lab or animal study, 2025, recent, not in people
Contexto y tradición
¿Por qué estas fuentes?
- La planta correcta. Debe indicar el nombre latino exacto de la especie. Nombres comunes como «ginseng» abarcan varias plantas.
- Primero los tipos de estudio más sólidos. Metaanálisis, luego ensayos aleatorizados en humanos, otros estudios en humanos, revisiones, estudios de laboratorio y en animales y, por último, enciclopedias.
- Más recientes primero. Dentro de cada tipo, los estudios más recientes aparecen primero. Los clásicos más antiguos se indican como tales.
- Primero las personas, luego las probetas. Una afirmación solo puede tener evidencia sólida o moderada si la respalda un estudio en humanos. Los resultados solo de laboratorio o en animales siempre son preliminares.
- Fuentes fiables, sin retractaciones. Solo artículos revisados por pares e indexados en PubMed o Europe PMC. Se eliminan los artículos retractados.
- Equilibrado. Los estudios que no detectaron efectos se conservan y reducen el nivel de evidencia.
- Limitada y heterogénea. Un máximo de 12 fuentes por planta y 3 de una misma revista.
Consúltalo por tu cuenta
Esta información es educativa y no sustituye el consejo médico. Las plantas medicinales pueden interactuar con los medicamentos y no sustituyen un tratamiento. Consulta con tu médico antes de usar cualquier planta para un problema de salud.
¿Cómo se descubrió?