2026年10月21日(水) · 女性の健康
Chaste tree
Vitex agnus-castus
A Mediterranean shrub whose pepper-like berries connect ancient women’s remedies with modern research on premenstrual symptoms.
体内で作用する部位
- 生殖器系
- 脳
伝統の知恵
アーユルヴェーダ初心者
Vitex agnus-castus has no established classical Sanskrit identity; Nirgundi ordinarily refers to Vitex negundo, a different species. The energetics given here are a contemporary Ayurvedic interpretation, not a classical attribution, and powdered chaste-tree fruit should not be represented as a classical Nirgundi churna or kashaya.
味(ラサ)
ドーシャのバランス
さまざまな伝統での使い方
Contemporary Ayurvedic herbalists sometimes interpret the fruit as bitter-pungent and warming, tending to settle vata and kapha while increasing pitta. Its use for menstrual concerns is an incorporation of Western herbal practice, rather than an established classical Ayurvedic indication.
心を整える習慣
Pause beside a living chaste tree, or contemplate a picture of its violet flower spikes, and take three unhurried breaths. Let the ritual be one of attention rather than an invitation to self-prescribe a hormone-active herb.
活性成分
- DiterpenesSome isolated diterpenes show dopamine-receptor activity in laboratory studies, a possible contributor to effects on prolactin signaling.
- AgnusideAn iridoid glycoside used as a quality-control marker; its independent contribution to clinical benefits remains uncertain.
- CasticinA flavonoid used in extract characterization, with anti-inflammatory activity in laboratory research; its clinical contribution is unclear. Visual compound weights are illustrative emphasis, not measured composition or proven contributions to benefit.
現代の研究
詳しく見る
生育地
私が使っても安全?
この植物について
Chaste tree is a deciduous shrub or small tree in the mint family, native to the Mediterranean region and western Asia. It grows along streams and other seasonally moist places, and is cultivated in sunny gardens worldwide.
Its aromatic leaves divide into five to seven narrow leaflets, and its upright spikes carry small lilac to violet flowers. The flowers develop into dark, peppercorn-sized fruits, commonly called chasteberries, which are the principal medicinal part.
植物との出会い
Ancient Greek and Roman writers described chaste tree in connection with reproductive health and chastity; its reputation for suppressing sexual desire helped give it its common name, but that reputation is not established clinical evidence. European herbal traditions later used the fruits for menstrual complaints. Modern researchers investigated standardized fruit extracts after clinical observations suggested benefits for premenstrual symptoms, exploring effects on dopamine signaling and prolactin regulation rather than assuming that the berries simply supply female hormones.
伝統的な用途
- Relief of premenstrual discomfort, including irritability and breast tenderness.
- Support for irregular menstrual cycles.
- Use for menstrual-associated breast pain.
- Historical use to influence milk production; effectiveness and safety during breastfeeding are not established.
研究の詳細
Premenstrual symptom relief · 予備的
None of the supplied excerpts directly reports results for premenstrual symptom relief. The adolescent menstrual-disorder case series does not identify premenstrual symptom outcomes in the provided text.
Cyclic breast pain relief · 予備的
None of the supplied sources directly evaluates cyclic breast pain relief, so benefit or lack of benefit cannot be established from this source set.
Fertility support · 予備的
None of the supplied excerpts directly reports fertility outcomes such as ovulation, pregnancy, or live birth. The PCOS studies examine hormonal, metabolic, or menstrual measures, which do not establish improved fertility; the human trial excerpts also omit results.
使い方
- If considering it for PMS, choose a quality-tested fruit extract that specifies its preparation and standardization. Different extract strengths are not interchangeable.
- Some studied and European-authorized preparations use 20 mg of a specific dry extract once daily. This is not equivalent to 20 mg of powdered berries; follow the particular product instructions and professional advice.
- Track symptoms over two to three menstrual cycles and reassess after about three months. Seek advice if symptoms persist, worsen, or substantially affect daily life.
- Capsules, tablets, and tinctures are common preparations, but evidence mainly concerns particular extracts—not homemade berry tea.
安全性
- Possible adverse effects include nausea, abdominal discomfort, headache, acne, rash, and changes in menstrual bleeding.
- Avoid during pregnancy and breastfeeding. It is generally not recommended for children or adolescents without specialist advice.
- Consult a clinician first if you have a hormone-sensitive condition or a pituitary disorder. Chasteberry may affect prolactin regulation and could complicate assessment of an underlying problem.
- Long-term safety is not well established. Severe mood symptoms, unexplained bleeding, a breast lump, or persistent breast pain need medical evaluation.
医薬品との相互作用
- Possible interaction with hormonal contraceptives: clinical evidence is limited, but an effect on contraceptive action cannot be excluded. Discuss use with a pharmacist or prescriber.
- May interact with hormone therapy, fertility medicines, or antiestrogen treatments such as tamoxifen; avoid combining without specialist guidance.
- May oppose or alter the effects of dopamine-related medicines, including antipsychotics, metoclopramide, and dopamine agonists such as cabergoline.
出典
AIではなく、一定のルールで選んだ10件の出典に基づいています。
ヒトを対象とした研究
- [1]The effects of <i>Vitex agnus-castus</i> supplementation on inflammatory markers in women with PCOS: a randomized, double-blind, placebocontrolled trial
Research in pharmaceutical sciences · 2026
試験理由: Randomised human trial, 2026, recent, human data - [2]The Effect of Vitex Agnus - Castus Plant on Some Markers of Oxidative Stress, Lipid Profile and Insulin Resistance in Women with Polycystic Ovary Syndrome: A Randomized, Double-Blind Controlled Clinical Trial Study
JBRA assisted reproduction · 2026
試験理由: Randomised human trial, 2026, recent, human data - [3]Case Series: Real-Life Experience with Vitex Agnus-Castus Extract Ze 440 Medication in Adolescents
Complementary medicine research · 2026
ヒトを対象とした研究理由: Human study, 2026, recent, human data
総説・基礎研究
- [4]Deep Eutectic Solvent Based Microwave and Ultrasound Assisted Extraction of Bioactive Compounds From Vitex agnus-castus: Optimization and Antioxidant/Antibacterial Evaluation
Chemistry & biodiversity · 2026
試験管内・動物実験理由: Lab or animal study, 2026, recent, not in people - [5]Clinical evaluation of the efficacy of <i>Vitex agnus-castus</i> compared with cabergoline for the treatment of pseudopregnancy in the bitch
Frontiers in veterinary science · 2026
試験管内・動物実験理由: Lab or animal study, 2026, recent, not in people - [6]<i>Vitex Agnus-Castus</i> Extract Supplementation Enhanced Growth Performance, Hemato-Biochemical Parameters, Intestinal Histomorphometry, Flesh Composition, and Quality of Nile Tilapia, <i>Oreochromis niloticus</i>
Aquaculture nutrition · 2026
試験管内・動物実験理由: Lab or animal study, 2026, recent, not in people - [7]<i>Vitex agnus-castus</i> extract improved the endocrine profile and important gene expression in rat ovaries with polycystic ovary syndrome
Avicenna journal of phytomedicine · 2026
試験管内・動物実験理由: Lab or animal study, 2026, recent, not in people - [8]Immunomodulatory effects of dietary chaste tree (<i>Vitex agnus-castus</i> L.) extract in rainbow trout (<i>Oncorhynchus mykiss</i>)
Open veterinary journal · 2025
試験管内・動物実験理由: Lab or animal study, 2025, recent, not in people - [9]Anticancer Activity of <i>Vitex agnus-castus</i> Seed Extract on Gastric Cancer Cells
Nutrients · 2025
試験管内・動物実験理由: Lab or animal study, 2025, recent, not in people
これらの情報源を選んだ理由
- 正しい植物の同定. 正確なラテン語の種名を明記する必要があります。「ジンセン」のような一般名は、複数の植物を指します。
- エビデンスの強い研究形式順. メタアナリシス、ヒトを対象としたランダム化試験、その他のヒト研究、総説、試験管内・動物実験、最後に百科事典の順に優先します。
- 新しい順. 同じ種類では、新しい論文ほど上位に表示されます。古い代表的な論文には、その旨を表示しています。
- 試験管よりヒトの研究を重視. 根拠が「強い」または「中程度」と評価されるには、ヒトを対象とした研究による裏付けが必要です。試験管内・動物実験の結果のみの場合は、常に「予備的」と評価されます。
- 信頼性が高く、撤回されていない. PubMedまたはEurope PMCに収載された査読済み論文のみを使用します。撤回された論文は除外します。
- バランス良好. 効果が認められなかった研究も残し、評価を下げる要因として反映します。
- 限定的でばらつきあり. 出典は植物ごとに最大12件、同じ学術誌からは最大3件です。
この情報は学習を目的としており、医療上の助言ではありません。薬草は薬と相互作用することがあり、治療の代わりにはなりません。健康上の問題に植物を使用する前に、医師に相談してください。
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