qua., 21 de out. de 2026 · Saúde da mulher
Chaste tree
Vitex agnus-castus
A Mediterranean shrub whose pepper-like berries connect ancient women’s remedies with modern research on premenstrual symptoms.
Onde atua no organismo
- Reprodutor
- Cérebro
Sabedoria tradicional
A dar os primeiros passos na Ayurveda
Vitex agnus-castus has no established classical Sanskrit identity; Nirgundi ordinarily refers to Vitex negundo, a different species. The energetics given here are a contemporary Ayurvedic interpretation, not a classical attribution, and powdered chaste-tree fruit should not be represented as a classical Nirgundi churna or kashaya.
Sabor (rasa)
Equilíbrio dos doshas
Entre tradições
Contemporary Ayurvedic herbalists sometimes interpret the fruit as bitter-pungent and warming, tending to settle vata and kapha while increasing pitta. Its use for menstrual concerns is an incorporation of Western herbal practice, rather than an established classical Ayurvedic indication.
Ritual de atenção plena
Pause beside a living chaste tree, or contemplate a picture of its violet flower spikes, and take three unhurried breaths. Let the ritual be one of attention rather than an invitation to self-prescribe a hormone-active herb.
Compostos ativos
- DiterpenesSome isolated diterpenes show dopamine-receptor activity in laboratory studies, a possible contributor to effects on prolactin signaling.
- AgnusideAn iridoid glycoside used as a quality-control marker; its independent contribution to clinical benefits remains uncertain.
- CasticinA flavonoid used in extract characterization, with anti-inflammatory activity in laboratory research; its clinical contribution is unclear. Visual compound weights are illustrative emphasis, not measured composition or proven contributions to benefit.
Investigação moderna
De perto
Onde cresce
É seguro para mim?
Sobre a planta
Chaste tree is a deciduous shrub or small tree in the mint family, native to the Mediterranean region and western Asia. It grows along streams and other seasonally moist places, and is cultivated in sunny gardens worldwide.
Its aromatic leaves divide into five to seven narrow leaflets, and its upright spikes carry small lilac to violet flowers. The flowers develop into dark, peppercorn-sized fruits, commonly called chasteberries, which are the principal medicinal part.
A descoberta
Ancient Greek and Roman writers described chaste tree in connection with reproductive health and chastity; its reputation for suppressing sexual desire helped give it its common name, but that reputation is not established clinical evidence. European herbal traditions later used the fruits for menstrual complaints. Modern researchers investigated standardized fruit extracts after clinical observations suggested benefits for premenstrual symptoms, exploring effects on dopamine signaling and prolactin regulation rather than assuming that the berries simply supply female hormones.
Usos tradicionais
- Relief of premenstrual discomfort, including irritability and breast tenderness.
- Support for irregular menstrual cycles.
- Use for menstrual-associated breast pain.
- Historical use to influence milk production; effectiveness and safety during breastfeeding are not established.
Detalhes da investigação
Premenstrual symptom relief · Preliminar
None of the supplied excerpts directly reports results for premenstrual symptom relief. The adolescent menstrual-disorder case series does not identify premenstrual symptom outcomes in the provided text.
Cyclic breast pain relief · Preliminar
None of the supplied sources directly evaluates cyclic breast pain relief, so benefit or lack of benefit cannot be established from this source set.
Fertility support · Preliminar
None of the supplied excerpts directly reports fertility outcomes such as ovulation, pregnancy, or live birth. The PCOS studies examine hormonal, metabolic, or menstrual measures, which do not establish improved fertility; the human trial excerpts also omit results.
Como se utiliza
- If considering it for PMS, choose a quality-tested fruit extract that specifies its preparation and standardization. Different extract strengths are not interchangeable.
- Some studied and European-authorized preparations use 20 mg of a specific dry extract once daily. This is not equivalent to 20 mg of powdered berries; follow the particular product instructions and professional advice.
- Track symptoms over two to three menstrual cycles and reassess after about three months. Seek advice if symptoms persist, worsen, or substantially affect daily life.
- Capsules, tablets, and tinctures are common preparations, but evidence mainly concerns particular extracts—not homemade berry tea.
Segurança
- Possible adverse effects include nausea, abdominal discomfort, headache, acne, rash, and changes in menstrual bleeding.
- Avoid during pregnancy and breastfeeding. It is generally not recommended for children or adolescents without specialist advice.
- Consult a clinician first if you have a hormone-sensitive condition or a pituitary disorder. Chasteberry may affect prolactin regulation and could complicate assessment of an underlying problem.
- Long-term safety is not well established. Severe mood symptoms, unexplained bleeding, a breast lump, or persistent breast pain need medical evaluation.
Interações medicamentosas
- Possible interaction with hormonal contraceptives: clinical evidence is limited, but an effect on contraceptive action cannot be excluded. Discuss use with a pharmacist or prescriber.
- May interact with hormone therapy, fertility medicines, or antiestrogen treatments such as tamoxifen; avoid combining without specialist guidance.
- May oppose or alter the effects of dopamine-related medicines, including antipsychotics, metoclopramide, and dopamine agonists such as cabergoline.
Fontes
Elaborado a partir de 10 fontes, escolhidas por regras fixas, não pela IA.
Estudos em humanos
- [1]The effects of <i>Vitex agnus-castus</i> supplementation on inflammatory markers in women with PCOS: a randomized, double-blind, placebocontrolled trial
Research in pharmaceutical sciences · 2026
EnsaioMotivo: Randomised human trial, 2026, recent, human data - [2]The Effect of Vitex Agnus - Castus Plant on Some Markers of Oxidative Stress, Lipid Profile and Insulin Resistance in Women with Polycystic Ovary Syndrome: A Randomized, Double-Blind Controlled Clinical Trial Study
JBRA assisted reproduction · 2026
EnsaioMotivo: Randomised human trial, 2026, recent, human data - [3]Case Series: Real-Life Experience with Vitex Agnus-Castus Extract Ze 440 Medication in Adolescents
Complementary medicine research · 2026
Estudo em humanosMotivo: Human study, 2026, recent, human data
Revisões e investigação laboratorial
- [4]Deep Eutectic Solvent Based Microwave and Ultrasound Assisted Extraction of Bioactive Compounds From Vitex agnus-castus: Optimization and Antioxidant/Antibacterial Evaluation
Chemistry & biodiversity · 2026
Laboratório / animaisMotivo: Lab or animal study, 2026, recent, not in people - [5]Clinical evaluation of the efficacy of <i>Vitex agnus-castus</i> compared with cabergoline for the treatment of pseudopregnancy in the bitch
Frontiers in veterinary science · 2026
Laboratório / animaisMotivo: Lab or animal study, 2026, recent, not in people - [6]<i>Vitex Agnus-Castus</i> Extract Supplementation Enhanced Growth Performance, Hemato-Biochemical Parameters, Intestinal Histomorphometry, Flesh Composition, and Quality of Nile Tilapia, <i>Oreochromis niloticus</i>
Aquaculture nutrition · 2026
Laboratório / animaisMotivo: Lab or animal study, 2026, recent, not in people - [7]<i>Vitex agnus-castus</i> extract improved the endocrine profile and important gene expression in rat ovaries with polycystic ovary syndrome
Avicenna journal of phytomedicine · 2026
Laboratório / animaisMotivo: Lab or animal study, 2026, recent, not in people - [8]Immunomodulatory effects of dietary chaste tree (<i>Vitex agnus-castus</i> L.) extract in rainbow trout (<i>Oncorhynchus mykiss</i>)
Open veterinary journal · 2025
Laboratório / animaisMotivo: Lab or animal study, 2025, recent, not in people - [9]Anticancer Activity of <i>Vitex agnus-castus</i> Seed Extract on Gastric Cancer Cells
Nutrients · 2025
Laboratório / animaisMotivo: Lab or animal study, 2025, recent, not in people
Contexto e tradição
Porquê estas fontes?
- A planta certa. Tem de indicar o nome latino exato da espécie. Nomes comuns como «ginseng» abrangem várias plantas.
- Tipo de estudo com maior evidência primeiro. Meta-análises, seguidas de ensaios aleatorizados em humanos, outros estudos em humanos, revisões, estudos laboratoriais e em animais e, por fim, enciclopédias.
- Mais recentes primeiro. Em cada categoria, os artigos mais recentes aparecem primeiro. Os clássicos mais antigos estão identificados como tal.
- Pessoas antes de tubos de ensaio. Uma alegação só pode ter evidência Forte ou Moderada se for apoiada por um estudo em humanos. Resultados apenas de laboratório ou em animais são sempre Preliminares.
- Credíveis e não retratados. Apenas artigos revistos por pares e indexados no PubMed ou Europe PMC. Os artigos retratados são removidos.
- Equilibrado. Os estudos que não encontraram efeito são mantidos e reduzem o nível de evidência.
- Limitada e heterogénea. No máximo, 12 fontes por planta e 3 da mesma revista científica.
Consulte as fontes
Esta informação é educativa e não constitui aconselhamento médico. As plantas medicinais podem interagir com medicamentos e não substituem o tratamento. Fale com o seu médico antes de usar qualquer planta para um problema de saúde.
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