2026年10月21日周三 · 女性健康
Chaste tree
Vitex agnus-castus
A Mediterranean shrub whose pepper-like berries connect ancient women’s remedies with modern research on premenstrual symptoms.
在体内的作用部位
- 生殖系统
- 大脑
传统智慧
阿育吠陀新手
Vitex agnus-castus has no established classical Sanskrit identity; Nirgundi ordinarily refers to Vitex negundo, a different species. The energetics given here are a contemporary Ayurvedic interpretation, not a classical attribution, and powdered chaste-tree fruit should not be represented as a classical Nirgundi churna or kashaya.
味(rasa)
三大生命能量平衡
各传统视角
Contemporary Ayurvedic herbalists sometimes interpret the fruit as bitter-pungent and warming, tending to settle vata and kapha while increasing pitta. Its use for menstrual concerns is an incorporation of Western herbal practice, rather than an established classical Ayurvedic indication.
正念仪式
Pause beside a living chaste tree, or contemplate a picture of its violet flower spikes, and take three unhurried breaths. Let the ritual be one of attention rather than an invitation to self-prescribe a hormone-active herb.
活性成分
- DiterpenesSome isolated diterpenes show dopamine-receptor activity in laboratory studies, a possible contributor to effects on prolactin signaling.
- AgnusideAn iridoid glycoside used as a quality-control marker; its independent contribution to clinical benefits remains uncertain.
- CasticinA flavonoid used in extract characterization, with anti-inflammatory activity in laboratory research; its clinical contribution is unclear. Visual compound weights are illustrative emphasis, not measured composition or proven contributions to benefit.
现代研究
近距离观察
生长地区
我用安全吗?
植物介绍
Chaste tree is a deciduous shrub or small tree in the mint family, native to the Mediterranean region and western Asia. It grows along streams and other seasonally moist places, and is cultivated in sunny gardens worldwide.
Its aromatic leaves divide into five to seven narrow leaflets, and its upright spikes carry small lilac to violet flowers. The flowers develop into dark, peppercorn-sized fruits, commonly called chasteberries, which are the principal medicinal part.
探索过程
Ancient Greek and Roman writers described chaste tree in connection with reproductive health and chastity; its reputation for suppressing sexual desire helped give it its common name, but that reputation is not established clinical evidence. European herbal traditions later used the fruits for menstrual complaints. Modern researchers investigated standardized fruit extracts after clinical observations suggested benefits for premenstrual symptoms, exploring effects on dopamine signaling and prolactin regulation rather than assuming that the berries simply supply female hormones.
传统用途
- Relief of premenstrual discomfort, including irritability and breast tenderness.
- Support for irregular menstrual cycles.
- Use for menstrual-associated breast pain.
- Historical use to influence milk production; effectiveness and safety during breastfeeding are not established.
研究详情
Premenstrual symptom relief · 初步
None of the supplied excerpts directly reports results for premenstrual symptom relief. The adolescent menstrual-disorder case series does not identify premenstrual symptom outcomes in the provided text.
Cyclic breast pain relief · 初步
None of the supplied sources directly evaluates cyclic breast pain relief, so benefit or lack of benefit cannot be established from this source set.
Fertility support · 初步
None of the supplied excerpts directly reports fertility outcomes such as ovulation, pregnancy, or live birth. The PCOS studies examine hormonal, metabolic, or menstrual measures, which do not establish improved fertility; the human trial excerpts also omit results.
使用方法
- If considering it for PMS, choose a quality-tested fruit extract that specifies its preparation and standardization. Different extract strengths are not interchangeable.
- Some studied and European-authorized preparations use 20 mg of a specific dry extract once daily. This is not equivalent to 20 mg of powdered berries; follow the particular product instructions and professional advice.
- Track symptoms over two to three menstrual cycles and reassess after about three months. Seek advice if symptoms persist, worsen, or substantially affect daily life.
- Capsules, tablets, and tinctures are common preparations, but evidence mainly concerns particular extracts—not homemade berry tea.
安全性
- Possible adverse effects include nausea, abdominal discomfort, headache, acne, rash, and changes in menstrual bleeding.
- Avoid during pregnancy and breastfeeding. It is generally not recommended for children or adolescents without specialist advice.
- Consult a clinician first if you have a hormone-sensitive condition or a pituitary disorder. Chasteberry may affect prolactin regulation and could complicate assessment of an underlying problem.
- Long-term safety is not well established. Severe mood symptoms, unexplained bleeding, a breast lump, or persistent breast pain need medical evaluation.
药物相互作用
- Possible interaction with hormonal contraceptives: clinical evidence is limited, but an effect on contraceptive action cannot be excluded. Discuss use with a pharmacist or prescriber.
- May interact with hormone therapy, fertility medicines, or antiestrogen treatments such as tamoxifen; avoid combining without specialist guidance.
- May oppose or alter the effects of dopamine-related medicines, including antipsychotics, metoclopramide, and dopamine agonists such as cabergoline.
资料来源
依据 10 篇文献编写,文献按固定规则筛选,而非由 AI 选择。
人体研究
- [1]The effects of <i>Vitex agnus-castus</i> supplementation on inflammatory markers in women with PCOS: a randomized, double-blind, placebocontrolled trial
Research in pharmaceutical sciences · 2026
试验原因: Randomised human trial, 2026, recent, human data - [2]The Effect of Vitex Agnus - Castus Plant on Some Markers of Oxidative Stress, Lipid Profile and Insulin Resistance in Women with Polycystic Ovary Syndrome: A Randomized, Double-Blind Controlled Clinical Trial Study
JBRA assisted reproduction · 2026
试验原因: Randomised human trial, 2026, recent, human data - [3]Case Series: Real-Life Experience with Vitex Agnus-Castus Extract Ze 440 Medication in Adolescents
Complementary medicine research · 2026
人体研究原因: Human study, 2026, recent, human data
综述与实验室研究
- [4]Deep Eutectic Solvent Based Microwave and Ultrasound Assisted Extraction of Bioactive Compounds From Vitex agnus-castus: Optimization and Antioxidant/Antibacterial Evaluation
Chemistry & biodiversity · 2026
实验室/动物研究原因: Lab or animal study, 2026, recent, not in people - [5]Clinical evaluation of the efficacy of <i>Vitex agnus-castus</i> compared with cabergoline for the treatment of pseudopregnancy in the bitch
Frontiers in veterinary science · 2026
实验室/动物研究原因: Lab or animal study, 2026, recent, not in people - [6]<i>Vitex Agnus-Castus</i> Extract Supplementation Enhanced Growth Performance, Hemato-Biochemical Parameters, Intestinal Histomorphometry, Flesh Composition, and Quality of Nile Tilapia, <i>Oreochromis niloticus</i>
Aquaculture nutrition · 2026
实验室/动物研究原因: Lab or animal study, 2026, recent, not in people - [7]<i>Vitex agnus-castus</i> extract improved the endocrine profile and important gene expression in rat ovaries with polycystic ovary syndrome
Avicenna journal of phytomedicine · 2026
实验室/动物研究原因: Lab or animal study, 2026, recent, not in people - [8]Immunomodulatory effects of dietary chaste tree (<i>Vitex agnus-castus</i> L.) extract in rainbow trout (<i>Oncorhynchus mykiss</i>)
Open veterinary journal · 2025
实验室/动物研究原因: Lab or animal study, 2025, recent, not in people - [9]Anticancer Activity of <i>Vitex agnus-castus</i> Seed Extract on Gastric Cancer Cells
Nutrients · 2025
实验室/动物研究原因: Lab or animal study, 2025, recent, not in people
为何选用这些来源?
- 确认植物身份. 必须注明准确的拉丁种名。“人参”等俗名可能指多种植物。
- 证据最强的研究类型优先. 依次优先采用荟萃分析、人体随机试验、其他人体研究、综述、实验室与动物研究,最后是百科全书。
- 最新优先. 同类文献按发表时间由新到旧排序,早期经典文献会特别标注。
- 人体证据优先于试管实验. 只有人体研究支持的论断,证据等级才能评为“强”或“中等”。仅有实验室或动物研究结果的,一律评为“初步”。
- 来源可靠且未撤稿. 仅采用 PubMed 或 Europe PMC 收录的同行评审论文,并剔除已撤稿论文。
- 平衡. 未发现效果的研究也会保留,并降低证据等级。
- 有限且不一致. 每种植物最多引用12篇文献,同一期刊最多3篇。
本内容仅供科普,不构成医疗建议。草药可能与药物相互作用,不能替代治疗。使用任何植物应对健康问题前,请先咨询医生。
这是如何发现的?